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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PAK1IP1
All Species:
17.88
Human Site:
S369
Identified Species:
30.26
UniProt:
Q9NWT1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NWT1
NP_060376.2
392
43964
S369
T
K
E
S
G
L
I
S
T
K
K
R
K
M
V
Chimpanzee
Pan troglodytes
XP_518863
393
44017
S370
T
K
E
S
G
L
V
S
T
K
K
R
K
M
V
Rhesus Macaque
Macaca mulatta
XP_001087458
392
43967
S369
T
K
E
S
G
L
V
S
T
K
K
R
K
M
V
Dog
Lupus familis
XP_535884
391
43743
S371
T
K
G
N
T
V
V
S
T
K
K
R
K
M
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCE5
382
42097
T364
T
K
G
N
S
P
V
T
A
K
K
R
K
M
A
Rat
Rattus norvegicus
NP_001032433
382
42216
P364
T
K
R
N
S
P
A
P
A
K
K
R
K
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514604
358
39493
K341
Q
K
S
P
K
K
R
K
L
E
S
T
Q
E
T
Chicken
Gallus gallus
Q5ZKU8
369
41214
K352
R
I
V
P
A
K
R
K
L
E
A
P
L
Q
K
Frog
Xenopus laevis
Q68FJ6
363
40513
V346
K
E
A
S
E
T
Q
V
V
H
K
K
R
K
P
Zebra Danio
Brachydanio rerio
Q6TNS2
368
40882
D351
G
E
E
V
I
M
E
D
E
K
G
S
K
T
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001181466
538
58474
S476
S
M
V
A
F
S
I
S
V
K
G
R
S
F
G
Poplar Tree
Populus trichocarpa
XP_002318775
332
35851
H315
T
C
L
A
G
S
S
H
N
V
S
T
V
I
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_176683
345
37437
Q328
L
K
S
M
R
R
P
Q
I
G
K
Q
E
P
Q
Baker's Yeast
Sacchar. cerevisiae
P20484
468
53654
K447
K
K
I
M
F
G
E
K
K
K
L
N
K
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.1
85.4
N.A.
72.4
75.2
N.A.
65
63
60.4
53
N.A.
N.A.
N.A.
N.A.
27.7
Protein Similarity:
100
99.7
97.6
92.8
N.A.
83.9
83.4
N.A.
76.5
78.5
75
69.6
N.A.
N.A.
N.A.
N.A.
44.8
P-Site Identity:
100
93.3
93.3
66.6
N.A.
46.6
46.6
N.A.
6.6
0
13.3
20
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
86.6
N.A.
66.6
53.3
N.A.
20
6.6
33.3
33.3
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
26.2
N.A.
N.A.
27
20.9
N.A.
Protein Similarity:
46.1
N.A.
N.A.
47.9
37.8
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
20
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
15
8
0
8
0
15
0
8
0
0
0
22
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
15
29
0
8
0
15
0
8
15
0
0
8
8
0
% E
% Phe:
0
0
0
0
15
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
0
15
0
29
8
0
0
0
8
15
0
0
0
8
% G
% His:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
0
8
8
0
8
0
15
0
8
0
0
0
0
8
0
% I
% Lys:
15
65
0
0
8
15
0
22
8
65
58
8
58
15
15
% K
% Leu:
8
0
8
0
0
22
0
0
15
0
8
0
8
0
0
% L
% Met:
0
8
0
15
0
8
0
0
0
0
0
0
0
43
0
% M
% Asn:
0
0
0
22
0
0
0
0
8
0
0
8
0
0
0
% N
% Pro:
0
0
0
15
0
15
8
8
0
0
0
8
0
8
8
% P
% Gln:
8
0
0
0
0
0
8
8
0
0
0
8
8
8
15
% Q
% Arg:
8
0
8
0
8
8
15
0
0
0
0
50
8
0
0
% R
% Ser:
8
0
15
29
15
15
8
36
0
0
15
8
8
0
0
% S
% Thr:
50
0
0
0
8
8
0
8
29
0
0
15
0
8
8
% T
% Val:
0
0
15
8
0
8
29
8
15
8
0
0
8
0
29
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _